abstract：BACKGROUND:To investigate the microarray data on the gene expression profiles of intervertebral disc degeneration related to cytokine exposure. The purpose of the study was to identify the key genes that were differentially expressed in these disc cells compared to cells without inflammatory cytokine treatment, using b...

journal_title：Journal of neurosurgical sciences

authors： Liu C,Zhang JF,Sun ZY,Tian JW

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Results from surgical series of tuberculum and planum sphenoidale meningiomas tends to be heterogeneous. Sekhar-Mortazavi tumor classification system has been recently proposed in order to predict the surgical risk and outcome. METHOD:We retrospectively reviewed a consecutive series of tuberculum and planum...

journal_title：Journal of neurosurgical sciences

authors： Giammattei L,Messerer M,Belouaer A,Daniel RT

更新日期：2018-01-04 00:00:00

abstract：BACKGROUND:A radical surgery of spine metastases is not possible in many cases, especially by elder multi morbid patients. The modern CAVITY/coblation method offers a very good therapeutic alternative for such patients. The goal of this paper was to evaluate and present the method as well as the results of the treatmen...

journal_title：Journal of neurosurgical sciences

authors： Dabravolski D,EßER J,Lahm A,Merk H

更新日期：2017-12-01 00:00:00

abstract：:Chronic subdural hematoma pathophysiology has been extensively studied and discussed. In the last decades, optic and electron microscope observations have successfully described its histopathology and the ultrastructure of internal membranes. Moreover, recent biochemical studies have identified a number of important p...

journal_title：Journal of neurosurgical sciences

authors： Cecchini G

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to develop a strategy to determine a sound methodology for decision-making in lumbar spinal canal stenosis (LSCS). METHODS:This was a retrospective study of patients with LSCS to determine the rationale for those who underwent surgery and those who received conservative treatment. ...

journal_title：Journal of neurosurgical sciences

authors： Azimi P,Mohammadi HR,Benzel EC,Shahzadi S,Azhari S,Montazeri A

更新日期：2017-08-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) is the most common malignant primary brain neoplasm, notorious for being able to evade and suppress the immune-system. We present a new immunotherapeutic approach that can potentially overcome or circumvent many of the GBM laden obstacles for an efficient antitumor immune response. In thi...

journal_title：Journal of neurosurgical sciences

authors： Cohen-Inbar O,Reiter Y,Zaaroor M

更新日期：2017-08-01 00:00:00

abstract：:There is a growing body of evidence that the insulin-like growth factor-1 (IGF-1) is dynamically involved in the regulation of body homeostasis and glucose regulation. Traumatic brain injury (TBI) is considered to be a risk factor for Alzheimer's disease (AD). As alterations of IGF-1 have been implicated in both TBI a...

journal_title：Journal of neurosurgical sciences

authors： Zheng P,Tong W

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:First advocated by Santoni et al. in 2009, the cortical bone trajectory pedicle screw technique is an alternative to the traditional, convergent technique that shows comparable biomechanical features and potentially requires less aggressive tissue retraction. Aim of this therapy note is to describe this new ...

journal_title：Journal of neurosurgical sciences

authors： Gautschi OP,Garbossa D,Tessitore E,Langella F,Pecoraro MF,Marengo N,Bozzaro M,Beckman J,Berjano P

更新日期：2017-06-01 00:00:00

abstract：:Brain metastases are a common problem in solid malignancies and still represent a major cause of morbidity and mortality. With the ongoing improvement in systemic therapies, the expectations on the efficacy of brain metastases directed treatment options are growing. As local therapies against brain metastases continue...

journal_title：Journal of neurosurgical sciences

authors： Specht HM,Combs SE

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Peripheral nerve lesions in the upper limbs occur predominantly in reproductive-age men and are often caused by sharp objects. Microsurgery is the choice treatment for these injuries, and regeneration after surgery typically is evaluated with clinical and electrophysiological examinations. The aim of this st...

journal_title：Journal of neurosurgical sciences

authors： Marquez Neto OR,Freitas T,Mendelovitz P,Schetchtman N,Kessler I

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The availability of Flow Diverters and new endovascular techniques has greatly reduced the need and indications for bypass surgery. Nevertheless, there are situations where a bypass is the best option for a complex cerebrovascular problem. METHODS:Generally typical indications are giant aneurysms with a wid...

journal_title：Journal of neurosurgical sciences

authors： Cenzato M,Bortolotti C

更新日期：2016-01-20 00:00:00

abstract：:The traditional dilemma making surgery for diffuse low-grade gliomas (DLGGs) challenging is underlain by the need to optimize tumor resection in order to significantly increase survival versus the risk of permanent neurological morbidity. Development of neuroimaging led neurosurgeons to achieve tumorectomy according t...

journal_title：Journal of neurosurgical sciences

authors： Duffau H

更新日期：2015-12-01 00:00:00

abstract：:This article aims to describe the roles, operative strategies and outcomes of neuroablative procedures in treatment of movement disorders related to cerebral palsy (CP). The authors reviewed relevant medical literatures concerning ablative neurosurgical procedures for CP. Neurosurgery is an appropriate option for trea...

journal_title：Journal of neurosurgical sciences

authors： Sitthinamsuwan B,Nunta-Aree S

更新日期：2015-12-01 00:00:00

abstract：:Multidisciplinary efforts are being made to provide surgical teams with sensitive and specific tasks for language mapping in awake surgery. Researchers and clinicians have elaborated different tasks over time. A fair amount of work has been directed to study the neurofunctional correlates of some of these tasks, and t...

journal_title：Journal of neurosurgical sciences

authors： Rofes A,Spena G,Miozzo A,Fontanella MM,Miceli G

更新日期：2015-12-01 00:00:00

abstract：:Lumbar stenosis patients typically present with neurogenic claudication or radiculopathy. Studies have shown the benefit of surgical management of lumbar stenosis for patients who fail medical management. Surgical management traditionally involved an open laminectomy and foramenotomies. The emergence of minimally inva...

journal_title：Journal of neurosurgical sciences

authors： Johans SJ,Amin BY,Mummaneni PV

更新日期：2015-03-01 00:00:00

abstract：AIM:The novel YL-1 hollow needle aspiration drainage system is an effective minimally invasive treatment in chronic subdural hematoma (CSDH). In order to find the risk prognosis factors of chronic subdural hematoma (CSDH) performed by the novel YL-1 hollow needle aspiration drainage system, a logistic analysis of posto...

journal_title：Journal of neurosurgical sciences

authors： Zhang HZ,Wu W,She L,Shi XQ,Wang XD,Zhang X

更新日期：2014-03-01 00:00:00

abstract：:Spinal cord injury (SCI) inevitably extends beyond neurologic consequences. The relationship between the spinal cord and its control of other organ systems make SCI management complex, requiring treatment on a multisystem approach. Patients frequently have hemodynamic instability and respiratory insufficiency secondar...

journal_title：Journal of neurosurgical sciences

authors： Lo V,Esquenazi Y,Han MK,Lee K

更新日期：2013-12-01 00:00:00

abstract：AIM:The aim of this study was to study the effect of preconditioning with hyperbaric oxygen on neural cell apoptosis after spinal cord injury in rats at different times, and to study the mechanism of neuroprotection with hyperbaric oxygen preconditioning after spinal cord injury. METHODS:Fifty-five adult Sprague-Dawle...

journal_title：Journal of neurosurgical sciences

authors： Lu PG,Feng H,Yuan SJ,Zhang RW,Li M,Hu R,Liu ZS,Yin J

更新日期：2013-09-01 00:00:00

abstract：AIM:The aim of this paper was to provide a comprehensive review of literature regarding the classification systems and surgical management of thoracolumbar spine trauma. METHODS:A Pubmed search of "thoracolumbar", "spine", "fracture" was used on January 05, 2013. Exclusionary criteria included non-Human studies, case ...

journal_title：Journal of neurosurgical sciences

authors： Ghobrial GM,Jallo J

更新日期：2013-06-01 00:00:00

abstract：AIM:Recent experimental studies have suggested that chemokines, a subclass of chemoattractant cytokines which play an important role in regulating leukocyte migration and intercellular communication, participate in brain responses of traumatic injury. Fractalkine (CX3CL1) is a peculiar chemokine, the only one with a CX...

journal_title：Journal of neurosurgical sciences

authors： Gaetani P,Pisano P,Solinas G,Colombo P,Destro A,Levi D,Aimar E,Rodriguez R,Baena Y,Allavena P

更新日期：2013-03-01 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive electrophysiological method to modulate cortical excitability. As such, rTMS can be used in conjunction with conventional physiotherapy or occupational therapy to facilitate rehabilitation of motor function in patients with focal brain lesions. This...

journal_title：Journal of neurosurgical sciences

authors： Paquette C,Thiel A

更新日期：2012-12-01 00:00:00

abstract：:Primary cerebellar glioblastoma multiforme (GBM) is a rare tumor in adults that accounts for just 1% of all cases of GBM. Cerebellar GBMs are not yet completely understood also as far as the prognosis. We report a case of cerebellar GBM in a 27-year-old woman. Magnetic resonance imaging (MRI) showed a 3x3.6 cm-sized, ...

journal_title：Journal of neurosurgical sciences

authors： Hernandez-Gonzalez G,Marchione P,De Angelis F,Giannone C,Kouleridou A,Spallone A

更新日期：2012-12-01 00:00:00

abstract：AIM:Mesenchymal stem cells (MSCs) migrate in response to chemokines and possess extensive tropism for experimental glioma. Antitumor effects have been reported following intracranial and intravenous administration of gene-modified MSCs. Among the different routes for cell transplant, the intraventricular (IV) approach ...

journal_title：Journal of neurosurgical sciences

authors： Panciani PP,Fontanella M,Tamagno I,Battaglia L,Garbossa D,Inghirami G,Fagioli F,Pagano M,Ducati A,Lanotte M

更新日期：2012-09-01 00:00:00

abstract：:Tumor related fractures of the spine frequently dictate surgical management. The most critical factors influencing the need and type of surgery are degree of epidural cord compression, radiosensitivity of the tumor, presence of spinal instability and patient medical status/ estimated survivorship. There is a wide spec...

journal_title：Journal of neurosurgical sciences

authors： Papanastassiou ID,Aghayev K,Saleh E,Gerochristou M,Vrionis FD

更新日期：2012-06-01 00:00:00

abstract：:Minimally invasive spine surgery is a rapidly developing field that has the potential to decrease surgical morbidity and improve recovery compared to traditional spinal approaches. Minimally invasive approaches have been developed for all regions of the spine, but have been best documented for degenerative conditions ...

journal_title：Journal of neurosurgical sciences

authors： Gandhi SD,Anderson DG

更新日期：2012-03-01 00:00:00

abstract：:The brainstem is an uncommon site for a brain abscess. It accounts for less than 4% of all posterior cranial fossa abscesses, and less than 1% of all intracranial abscesses. The pons is the most common site for these abscesses. The aim of the present report was to describe the case of a Brazilian Amazon man with a bra...

journal_title：Journal of neurosurgical sciences

authors： Hermes de N Jr,Rodrigues Pereira EL,Castro Ribeiro DE,Da Silva Mello G,Hartuique Rodrigues DC,Crociati Meguins L,Toyoki Motoki Teixeira VH,De Souza Rogério J

更新日期：2011-12-01 00:00:00

abstract：:Recurrent radicular pain after lumbar micro-discectomy may lead to reduced quality of life of the patient. Lumbar epidural fibrosis is believed to be one of the mechanisms involved in the genesis of the pain. The use of absorbable gel temporarily separating disc remnants, muscle or bone structures from the nerve roots...

journal_title：Journal of neurosurgical sciences

authors： Fransen P

更新日期：2011-09-01 00:00:00

abstract：:Starting from January 2008, we systematically irrigated the surgical wounds of patients undergoing spine surgery with a solution of povidone-iodine and hydrogen peroxide. We prospectively recorded the clinical data of patients who underwent spine surgery during 2008 and we compared the results with retrospectively rev...

journal_title：Journal of neurosurgical sciences

authors： Ulivieri S,Toninelli S,Petrini C,Oliveri G

更新日期：2011-06-01 00:00:00

abstract：:Arteriovenous malformations (AVM) can occur in the entire central nervous system with a predilection of the supratentorial intracranial compartment. Intracerebral hemorrhage is the most common clinical presentation of AVM and associated with a high morbidity and mortality rate. Correct management of these lesions is t...

journal_title：Journal of neurosurgical sciences

authors： Sandalcioglu IE,Wanke I,Zappala V,Forsting M,Sure U

更新日期：2011-03-01 00:00:00

abstract：:Isolated abducens nerve palsy following lumbar puncture is a very rare condition. In this case we discussed the probable causes of abducens nerve palsy and review the mechanism of action in anatomical relevant literature. A 53-year old hypertensive female patient with a saccular aneursym on the left middle cerebral ar...

journal_title：Journal of neurosurgical sciences

authors： Yaman ME,Ayberk G,Eylen A,Ozveren MF

更新日期：2010-09-01 00:00:00

abstract：:Echinococcosis is a potentially fatal parasitic disease that can affect many animals and humans. The disease results from infection by tapeworm larvae of the genus Echinococcus--notably, E. granulosus, E. multilocularis, E. vogeli andE. oligarthrus. Cyst hydatid disease is usually seen in adults, and mainly affects li...

journal_title：Journal of neurosurgical sciences

authors： Altas M,Aras M,Serarslan Y,Davran R,Evirgen O,Yilmaz N

更新日期：2010-06-01 00:00:00

abstract：:The authors report a case of intracranial tumor in a 60 year female, previously asymptomatic presenting with altered sensorium following a road traffic accident. Imaging showed a small left frontotemporal contusion along with a large right frontoparietal extra axial mass lesion suggestive of a meningioma. Patient impr...

journal_title：Journal of neurosurgical sciences

authors： Sai Kiran NA,Kasliwal MK,Gupta A,Mridha AR,Sharma MC,Sharma BS

更新日期：2009-12-01 00:00:00

abstract：AIM:Ossification of the posterior longitudinal ligament (OPLL) is a pathological ossification of the ligament that causes slowly progressive myelo-radiculopathy in adults. Because of long-standing compression of the spinal cord by OPLL, functional prognosis may not always be favorable. Efforts have been made in recent ...

journal_title：Journal of neurosurgical sciences

authors： Inamasu J,Guiot BH

更新日期：2009-09-01 00:00:00

abstract：AIM:Fractionated stereotactic radiotherapy is an alternative to radiosurgery or conformal radiotherapy when meningiomas are surgically inaccessible, incompletely removed, or recurrent. The authors report preliminary results of a feasible trial on hypofractionated stereotactic radiotherapy (hFSRT) in patients (pts) with...

journal_title：Journal of neurosurgical sciences

authors： Trippa F,Maranzano E,Costantini S,Giorni C

更新日期：2009-03-01 00:00:00

abstract：AIM:Tethered cord syndrome (TCS) is a stretch-induced functional disorder of the spinal cord, which is directly related to filum fixation. Classic surgical approaches to the filum involve open surgery and include varying amounts of spinal bone removal. In an effort to reduce the morbidity and mortality of these procedu...

journal_title：Journal of neurosurgical sciences

authors： Mourgela S,Anagnostopoulou S,Sakellaropoulos A,Koulousakis A,Warnke JP

更新日期：2008-09-01 00:00:00

abstract：:Subependymoma was first described by Scheinker in 1945; it frequently occurs in the ventricles and rarely in the spinal canal representing 0.7% of all central nervous system tumours. Most of these intraventricular tumours are subclinical entities, remaining of small size and discovered at autopsy with 0.4%incidence. W...

journal_title：Journal of neurosurgical sciences

authors： Romoli S,Abbruzzese A,Castagna M,Becherini F,Parenti G

更新日期：2007-06-01 00:00:00

abstract：:The improved knowledge of clinical and emodynamical aspects of extracranial arteriovenous malformations in the 18 th century provided a foundation for the understanding and treatment of cerebrovascular pathology. It was not until the late 19 th century that detailed clinicopathological reports of intracranial arteriov...

journal_title：Journal of neurosurgical sciences

authors： Perrini P,Nannini T,Di Lorenzo N

更新日期：2007-03-01 00:00:00

abstract：:A case of a 61-year-old female patient who presents with the clinical triad of normal pressure hydrocephalus (NPH), abnormal gait, urinary incontinence and dementia. On CT scanning, she is found to have a large arachnoid cyst which mimicked the syndrome of NPH. This is also the 60th published case of arachnoid cyst pr...

journal_title：Journal of neurosurgical sciences

authors： Ramtahal J

更新日期：2006-09-01 00:00:00

abstract：:Spontaneous infarction of the ligamentum flavum is a very rare cause of mielo-radicular compression. In the literature only four cases are reported, all characterized by a clinical history of slowly progressive mielo-radiculopathy and good outcome after surgical treatment. A 70 year-old female patient presented with a...

journal_title：Journal of neurosurgical sciences

authors： Albanese A,Braconi A,Anile C,Mannino S,Sabatino G,Mangiola A

更新日期：2006-06-01 00:00:00

abstract：AIM:The challenge in large cranial base meningiomas is total resection of the tumor with the least possible mortality and morbidity. During the last two decades the technical approaches for anterior skull base tumors have shown a considerable progress, providing a wide exposure with minimal brain retraction. The purpos...

journal_title：Journal of neurosurgical sciences

authors： Tzortzidis F,Partheni M,Voulgaris S,Gousias K,Konstantinou D

更新日期：2005-09-01 00:00:00